منابع مشابه
Not so sweet malignant transformation.
A critical requirement for the success of a multicellular organism is the ability to exquisitely regulate the growth of its component cells. Tumors, also called neoplasias, occur when that regulation is disturbed; the term neoplasia simply means “new growth.” The pathology community classifies neoplasias as benign or malignant based on morphologic features of the cells in the tumor, the presenc...
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The pace of life has changed. And that doesn’t just extend to fast food and media ‘sound bites’; it seems we now expect our science to be delivered in instant, bite-sized pieces, too. I recently wrote a mini-review for a well-respected journal. This journal maintains a high standard for such articles and has them peer-reviewed before accepting them. The reviewers’ comments were mostly very help...
متن کاملThe not-so-sweet side of fructose.
sieving of three neutral polysaccharides, polyethylene oxide and bikunin in rat: Effects of molecular size and conformation. Acta Physiol (Oxf) 191: 237–246, 2007 10. Tojo A, Onozato ML, Ha H, Kurihara H, Sakai T, Goto A, Fujita T, Endou H: Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats. Histochem Cell Biol 116: 269–276, 2001 11. Park CH, Maack T: Albumin absor...
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Intervention: On admission, patients were randomly assigned to strict normalization of blood glucose levels (80 to 110 mg per deciliter [4.4 to 6.1 mmol per liter]) with the use of insulin infusion or to conventional therapy (insulin administered when the blood glucose level exceeded 215 mg per deciliter [12 mmol per liter], with the infusion tapered when the level fell below 180 mg per decilit...
متن کاملPerinatal nephron programming is not so sweet in maternal diabetes.
Development of the permanent, metanephric kidney begins at approximately embryonic day 11 (E11) in mice, E12 in rats, and during the fourth through fifth gestational weeks in humans. During these stages, the ureteric bud projects from the mesonephric duct and enters the metanephric anlage, whereupon buds branch repeatedly and ultimately form the collecting duct system of the mature kidney (and ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2014
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1415576111